Internal Job Title – Senior Scientist I

Position locations: Cambridge, MA, onsite

The Chemical Genetics group in Cambridge, MA, is seeking a highly motivated, curious, and innovative scientist to boost our endeavor in the discovery, development, and characterization of small molecules affecting defined phenotypes with the goal of uncovering and validating novel therapeutics and drug targets. We are a highly collaborative and global group of chemists and biologists dynamically exploring the interface of chemistry and biology in initiating, leading, and progressing team-oriented projects in early drug discovery. This group is part of the larger Discovery Sciences (DSc) department that encompasses the full-spectrum of sophisticated capabilities needed to succeed in a state-of-the-art drug discovery biopharma laboratory. This position will collaborate closely with research teams within DSc, as well as across diverse Disease Areas.

Your key responsibilities:

• Applying your chemistry expertise to prosecute on hits from biochemical or phenotypic screens
• Small molecule design, multi-step synthesis and optimization, including exploration of structure activity relationships and synthesis of chemical probes for addressing impactful biological and conceptual questions.
• Frequent oral data communication/presentation across a spectrum of skillsets and levels, engagement of internal and external partners and collaborators.
• Organizational skills for design, tracking, and communication experiments and data.

Essential requirements:

• A B.S. or M.S. degree in Chemistry and 5+ years experience in academia or industry, with demonstrated ability in one or more of the following: synthetic organic chemistry, drug discovery, chemical biology, chemical probe design. This is not a PhD-level position.
• Proficiency in broad array of chemical synthesis techniques, chemical probe design and development, characterization and purification of new molecular entities/modalities. Experience with common spectroscopy (NMR, IR, UV, MS), analytical techniques and chromatography purification systems is required

• A comprehensive knowledge of modern organic synthetic methods; medicinal chemistry, chemical biology knowledge is a plus
• Track record of innovation, efficient hypothesis testing, and execution of outside-the-box approaches to tackle challenging scientific problems.
• Ability to design, perform, analyze, and interpret data to propose next steps in both experimental and project design and overall strategy.
• Highly self-motivated, fast learner, flexible, innovative and fearless.
• Thrives in an interdisciplinary, team-oriented and collaborative environments.

Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity and Inclusion / EEO: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $97,600 to $146,400/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical locations, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network